EP-1298: Local Relapse By Biological Subtypes In Breast Cancer Patients
نویسندگان
چکیده
منابع مشابه
Breast cancer subtypes and outcome after local and regional relapse.
BACKGROUND To evaluate the outcome of breast cancer patients after locoregional recurrence (LRR) according to tumor biological features evaluated at first diagnosis and at the time of recurrence. PATIENTS AND METHODS We collected information on all consecutive breast cancer patients operated at the European Institute of Oncology between 1994 and 2005. The tumor characteristics and subsequent ...
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Patients with isolated locoregional recurrences of breast cancer have a high risk of distant metastasis and death from cancer. The main objective in this clinical setting is curative treatment, which consists of radical surgery with or without complementary radiotherapy. The targeted localisations include soft tissue of the ipsilateral conserved breast or of the chest wall, mastectomy scar or s...
متن کاملBreast cancer subtypes and the risk of local and regional relapse.
PURPOSE The risk of local and regional relapse associated with each breast cancer molecular subtype was determined in a large cohort of patients with breast cancer. Subtype assignment was accomplished using a validated six-marker immunohistochemical panel applied to tissue microarrays. PATIENTS AND METHODS Semiquantitative analysis of estrogen receptor (ER), progesterone receptor (PR), Ki-67,...
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We explored whether the five previously reported molecular subtypes in breast cancer show a preference for organ-specific relapse and searched for molecular pathways involved. The "intrinsic" gene list describing the subtypes was used to classify 344 primary breast tumors of lymph node-negative patients. Fisher exact tests were used to determine the association between a tumor subtype and a par...
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ژورنال
عنوان ژورنال: Radiotherapy and Oncology
سال: 2018
ISSN: 0167-8140
DOI: 10.1016/s0167-8140(18)31608-6